Rats Exposed to Excess Sucrose During a Critical Period Develop Inflammation and Express a Secretory Phenotype of Vascular Smooth Muscle Cells
There is transient hypertension at the end of the CP that is accompanied by inflammation and a change in the phenotype of VSMC to the secretory phenotype. The inflammatory changes could act as epigenetic signals to determine the development of hypertension when animals reach adulthood.
Authors
- María Esther Rubio-Ruiz (ORCID: https://orcid.org/0000-0002-8844-2078)
- Gabriela Zarco
- Elizabeth Soria‐Castro (ORCID: https://orcid.org/0000-0001-8050-1961)
- Elizabeth Carreón‐Torres (ORCID: https://orcid.org/0000-0003-3600-249X)
- Vicente Castrejón-Téllez (ORCID: https://orcid.org/0000-0002-8518-6961)
- Israel Pérez-Torres (ORCID: https://orcid.org/0000-0001-6510-2954)
- Verónica Guarner‐Lans (ORCID: https://orcid.org/0000-0002-2655-7590)
- Agustina Cano-Martı́nez (ORCID: https://orcid.org/0000-0002-6703-2176)
- Oscar Emanuel Grimaldo
Institutions
- Instituto Nacional de Cardiología (MX)
Publication Details
- Journal
- Metabolites
- Published
- 2024-10-17
- DOI
- https://doi.org/10.3390/metabo14100555
- Citations
- 3
- Primary Topic
- Birth, Development, and Health
- Type
- article
- Field-Weighted Citation Impact
- 3.33