Intravenous paracetamol-related loss of consciousness at induction of anesthesia: A case report

Paracetamol (Acetaminophen) is an analgesics, antipyretic, and non-steroidal anti-inflammatory drugs. It is known to be one of the commonly used analgesics globally. Intravenous paracetamol has been frequently used in patients as analgesics and antipyretics. In therapeutic doses, paracetamol is well-tolerated and devoid of severe adverse reactions. However, significant adverse reactions associated with intravenous paracetamol may occur rarely. Nausea, vomiting, and constipation are known to be the common side effects of paracetamol. Other side effects include pain and reaction at the site of injection. The adverse reactions of paracetamol are as follows; hypotension, malaise, hypersensitivity reaction, elevation of liver enzymes, and thrombocytopenia. In our center, we found a case of intravenous paracetamol-related loss of consciousness at induction of anesthesia in a patient booked for myomectomy.