Morphometric measurements of intraoral anatomy in children with Beckwith-Wiedemann syndrome: a novel approach
Intraoral morphometric measurements are associated with phenotypic burden in BWS. Tongue morphology varies across the BWS spectrum, with IC2 LOM having wider tongues and mouths, and pUPD11 having narrower mouths. Tongue ridging is more common in those selected for surgery. Intraoral morphometric measurements may be safely obtained at low costs across centers caring for children with BWS or others at risk of upper airway obstruction.
Authors
- Jonathan Sussman (ORCID: https://orcid.org/0000-0002-7702-8816)
- Richard J. Schwab
- Dominic J. Romeo (ORCID: https://orcid.org/0000-0003-0150-4174)
- Jesse A. Taylor (ORCID: https://orcid.org/0000-0003-2827-5471)
- Jinggang J. Ng (ORCID: https://orcid.org/0000-0002-1180-7526)
- Andrew M. George (ORCID: https://orcid.org/0000-0001-6661-3924)
- Meagan Wu (ORCID: https://orcid.org/0000-0002-7995-7256)
- Christopher M. Cielo︎ (ORCID: https://orcid.org/0000-0001-5761-6373)
- Jennifer M. Kalish (ORCID: https://orcid.org/0000-0003-1500-9713)
- Manisha Banala (ORCID: https://orcid.org/0000-0002-8822-8135)
- Andrew Wiemken
Institutions
- Children's Hospital of Philadelphia (US)
- University of Pennsylvania (US)
Publication Details
- Journal
- Orphanet Journal of Rare Diseases
- Published
- 2024-10-17
- DOI
- https://doi.org/10.1186/s13023-024-03350-3
- Citations
- 2
- Primary Topic
- Genetic Syndromes and Imprinting
- Type
- article
- Field-Weighted Citation Impact
- 1.10