Investigating the feasibility of <sup>18</sup>F‐flortaucipir PET imaging in the antemortem diagnosis of primary age‐related tauopathy (PART): An observational imaging‐pathological study
<sup>18</sup>F-flortaucipir (FTP) PET scans were analyzed for diagnosing PART antemortem. 32% of PART cases had minimal/mild FTP uptake in the left inferior temporal lobe. Similar to PART FTP uptake was found in 62% of control subjects. No specific uptake pattern was found, challenging in vivo PART diagnosis.
Authors
- Val J. Lowe (ORCID: https://orcid.org/0000-0002-5612-1667)
- Clifford R. Jack (ORCID: https://orcid.org/0000-0001-7916-622X)
- Keith A. Josephs (ORCID: https://orcid.org/0000-0003-2930-8634)
- Dennis W. Dickson (ORCID: https://orcid.org/0000-0001-7189-7917)
- Ronald Carl Petersen (ORCID: https://orcid.org/0000-0002-8178-6601)
- Nha Trang Thu Pham
- Anna Lavrova (ORCID: https://orcid.org/0009-0001-7521-7082)
- Aivi T. Nguyen (ORCID: https://orcid.org/0000-0003-1809-9451)
- Ruth A. Ross
- Jennifer L. Whitwell (ORCID: https://orcid.org/0000-0001-6914-1563)
- Ryota Satoh (ORCID: https://orcid.org/0000-0002-3418-2987)
Institutions
- Mayo Clinic (US)
- Jacksonville College (US)
- Mayo Clinic in Florida (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-10-17
- DOI
- https://doi.org/10.1002/alz.14301
- Citations
- 3
- Primary Topic
- Advanced Neuroimaging Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 1.21
Funders
- Elsie and Marvin Dekelboum Family Foundation
- National Institutes of Health