Increased Red Cell Superoxide Dismutase Activity Is Associated with Cancer Risk: A Hidaka Cohort Study
Our study is the first to show that increased R-SOD activity is associated with a significantly higher cancer risk in men but not in women. Antioxidative enzymes such as SOD are essential for maintaining cellular redox balance. Their roles in cancer development and prevention are yet to be fully elucidated.
Authors
- Takeshi Tsujino
- Shinichiro Tanaka (ORCID: https://orcid.org/0000-0003-4217-6859)
- Ken‐ichi Hirata (ORCID: https://orcid.org/0000-0002-6782-3031)
- Tatsuro Ishida (ORCID: https://orcid.org/0000-0002-1724-0057)
- Yoshio Fujioka (ORCID: https://orcid.org/0000-0002-9733-7974)
Institutions
- Hyogo University of Health Sciences (JP)
- Kobe Gakuin University (JP)
- Kobe Medical Center (JP)
- Toyooka Hospital (JP)
- Kobe University (JP)
Publication Details
- Journal
- Cancer Research Communications
- Published
- 2024-10-17
- DOI
- https://doi.org/10.1158/2767-9764.crc-24-0301
- Primary Topic
- Glutathione Transferases and Polymorphisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00