Comparing Conservative and Early Surgical Treatments for Pyogenic Spondylodiskitis: An International Propensity Score–Matched Retrospective Outcome Analysis
The study indicates that early surgical intervention may be more effective than conservative management in reducing mortality and hospital stay for patients with primary pyogenic spondylodiskitis. These findings highlight the need for prospective trials and more definitive treatment guidelines.
Authors
- Barrie Lyell
- Hariharan Subbiah Ponniah (ORCID: https://orcid.org/0000-0002-5471-9120)
- Benjamin M. Davies (ORCID: https://orcid.org/0000-0003-0591-5069)
- Ehab Shiban (ORCID: https://orcid.org/0000-0001-7427-3034)
- Daniele Ramsay (ORCID: https://orcid.org/0000-0001-5585-1118)
- Bernhard Meyer (ORCID: https://orcid.org/0000-0001-6486-7955)
- Maria Wostrack (ORCID: https://orcid.org/0000-0001-6439-3665)
- Santhosh G. Thavarajasingam (ORCID: https://orcid.org/0000-0002-9274-0350)
- Andreas Kyriacou Demetriades (ORCID: https://orcid.org/0000-0002-2004-9448)
- Frank Kandziora (ORCID: https://orcid.org/0000-0002-5086-8612)
- Jonathan Neuhoff (ORCID: https://orcid.org/0009-0007-4060-4748)
- Rebecca Sutherland (ORCID: https://orcid.org/0000-0001-5214-9630)
- Florian Ringel (ORCID: https://orcid.org/0000-0003-3132-7543)
- Hugh McCaughan (ORCID: https://orcid.org/0000-0002-4090-9054)
- Olga Berkulian
- Andreas Krämer (ORCID: https://orcid.org/0000-0003-0168-0178)
- Ann-Kathrin Joerger
Institutions
- NHS Lothian (GB)
- Johannes Gutenberg University Mainz (DE)
- Western General Hospital (GB)
- University Hospital Augsburg (DE)
- Cambridge University Hospitals NHS Foundation Trust (GB)
- TUM Klinikum (DE)
- University Medical Center of the Johannes Gutenberg University Mainz (DE)
- Berufsgenossenschaftliche Unfallklinik Frankfurt am Main (DE)
- Imperial College London (GB)
- University of Edinburgh (GB)
Publication Details
- Journal
- Neurosurgery
- Published
- 2024-10-17
- DOI
- https://doi.org/10.1227/neu.0000000000003223
- Citations
- 9
- Primary Topic
- Infectious Diseases and Tuberculosis
- Type
- article
- Field-Weighted Citation Impact
- 5.15
Funders
- Wellcome Trust