Efficacy of Quercetin and Quercetin Loaded Chitosan Nanoparticles Against Cisplatin-Induced Renal and Testicular Toxicity via Attenuation of Oxidative Stress, Inflammation, and Apoptosis
Our findings suggest that both QUE and QUE.NPs modulated emotional disturbance and improved testicular and renal functions via modulation of oxidation, inflammation, and apoptosis. However, QUE.NPs performed better than QUE-treated rats.
Authors
- Dina F. Mansour (ORCID: https://orcid.org/0000-0002-5656-2462)
- Hamad S. Alyami (ORCID: https://orcid.org/0000-0003-3513-4976)
- Riham A. El‐Shiekh (ORCID: https://orcid.org/0000-0002-3179-3352)
- Heba M. A. Khalil (ORCID: https://orcid.org/0000-0001-6008-2157)
- Alaa F. Bakr (ORCID: https://orcid.org/0000-0003-1184-3882)
- Mohamed Y. Mahmoud (ORCID: https://orcid.org/0000-0002-7084-2604)
- Mohammad H. Alyami (ORCID: https://orcid.org/0000-0003-2731-1071)
- Omneya Galal
Institutions
- Suez University (EG)
- Cairo University (EG)
- National Research Centre (EG)
- King Salman International University
- Galala University
- Najran University (SA)
- Ahram Canadian University (EG)
Publication Details
- Journal
- Pharmaceuticals
- Published
- 2024-10-17
- DOI
- https://doi.org/10.3390/ph17101384
- Citations
- 10
- Primary Topic
- Chemotherapy-induced organ toxicity mitigation
- Type
- article
- Field-Weighted Citation Impact
- 4.25
Funders
- Najran University