Spatial Dynamics of T- and B-Cell Responses Predicts Clinical Outcome of Resectable and Unresectable Hepatocellular Carcinoma
We revealed the spatial dynamics of T- and B-cell responses in HCC, which is closely associated with the clinical outcome after surgical resection or Atezo + Bev therapy.
Authors
- Hidenori Ojima (ORCID: https://orcid.org/0000-0001-9154-246X)
- Minoru Kitago (ORCID: https://orcid.org/0000-0002-4909-1199)
- Ken Yamazaki (ORCID: https://orcid.org/0000-0002-7220-7479)
- Michiie Sakamoto
- Takao Itoi (ORCID: https://orcid.org/0000-0002-9433-8437)
- Kathryn Effendi (ORCID: https://orcid.org/0000-0001-7844-1170)
- Hirohito Takeuchi (ORCID: https://orcid.org/0000-0002-2082-3202)
- Yutaka Kurebayashi (ORCID: https://orcid.org/0000-0003-3773-0851)
- Yohei Masugi (ORCID: https://orcid.org/0000-0002-6952-4043)
- Akihisa Ueno (ORCID: https://orcid.org/0000-0001-9428-4128)
- Katsutoshi Sugimoto (ORCID: https://orcid.org/0000-0001-6271-7806)
- Hanako Tsujikawa (ORCID: https://orcid.org/0000-0002-6389-430X)
- Koichiro Matsuda (ORCID: https://orcid.org/0009-0009-5125-1129)
- Yasushi Hasegawa (ORCID: https://orcid.org/0000-0002-4990-0419)
- Yuta Abe (ORCID: https://orcid.org/0000-0002-5840-8901)
- Rui Nomura
Institutions
- Tokyo Medical University (JP)
- Keio University (JP)
- Keio University Hospital (JP)
- Tokyo Medical University Hospital (JP)
- Tochigi Cancer Center (JP)
- Saitama Municipal Hospital (JP)
- National Hospital Organization (JP)
- National Hospital Organization Saitama Hospital
- International University of Health and Welfare (JP)
Publication Details
- Journal
- Clinical Cancer Research
- Published
- 2024-10-17
- DOI
- https://doi.org/10.1158/1078-0432.ccr-24-0479
- Citations
- 10
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 2.83
Funders
- Japan Agency for Medical Research and Development
- Foundation for Promotion of Cancer Research
- Japan Society for the Promotion of Science