Serum amyloid P (PTX2) attenuates hepatic fibrosis in mice by inhibiting the activation of fibrocytes and HSCs
Since HSCs serve as a major source of collagen type I-producing myofibroblasts and fibrocytes stimulate fibrosis, hSAP may become part of the therapy of liver fibrosis of different etiologies.
Authors
- Michael Krämer (ORCID: https://orcid.org/0000-0002-0251-2726)
- David A. Brenner (ORCID: https://orcid.org/0000-0003-2573-525X)
- Tatiana Kisseleva (ORCID: https://orcid.org/0000-0001-9107-2306)
- Raquel Weber (ORCID: https://orcid.org/0000-0001-5083-9988)
- David A. Brafman (ORCID: https://orcid.org/0000-0001-6131-2532)
- Jun Xu (ORCID: https://orcid.org/0000-0003-4221-5563)
- Kojiro Taura (ORCID: https://orcid.org/0000-0003-4164-3988)
- Yuzo Kodama (ORCID: https://orcid.org/0000-0003-1223-7147)
- Vivian Zhang (ORCID: https://orcid.org/0000-0002-5059-3399)
- Shu Chien (ORCID: https://orcid.org/0000-0003-0332-285X)
- Chunyan Jiang (ORCID: https://orcid.org/0000-0001-8757-6229)
- Mark Lupher (ORCID: https://orcid.org/0000-0002-2118-7156)
- Sadatsugu Sakane (ORCID: https://orcid.org/0000-0002-6306-4621)
- Min Cong
- Samuele DeMinicis
- Souradipta Ganguly
Institutions
- Marche Polytechnic University (IT)
- Capital Medical University (CN)
- Sanford Burnham Prebys Medical Discovery Institute (US)
- Kyoto University (JP)
- University of California San Diego (US)
- Gilead Sciences (United States) (US)
- Beijing Friendship Hospital (CN)
- Jacobs (United States) (US)
- Kitano Hospital (JP)
- Arizona State University (US)
- Kobe University (JP)
Publication Details
- Journal
- Hepatology Communications
- Published
- 2024-10-17
- DOI
- https://doi.org/10.1097/hc9.0000000000000557
- Citations
- 1
- Primary Topic
- Biomarkers in Disease Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.24