Mixed Th1/Th2/Th17 Responses Induced by Plant Oil Adjuvant-Based B. bronchiseptica Vaccine in Mice, with Mechanisms Unraveled by RNA-Seq, 16S rRNA and Metabolomics
Collectively, our results demonstrate the huge potential of E515-Bb vaccine candidates, thus highlighting the vegetable oil original adjuvant E515 as a promising agent for the development of new veterinary vaccines.
Authors
- Zizhe Hu (ORCID: https://orcid.org/0000-0002-4425-4470)
- Yee Huang
- Xuemei Cui (ORCID: https://orcid.org/0009-0004-2232-4484)
- Guolian Bao (ORCID: https://orcid.org/0000-0001-8327-9921)
- Yan Liu (ORCID: https://orcid.org/0000-0002-0446-4633)
- Tuanyuan Shi
- Quanan Ji
- Qiuyu Xiang
Institutions
- Zhejiang A & F University (CN)
- Animal Science Research Institute (CN)
- ZheJiang Academy of Agricultural Sciences (CN)
Publication Details
- Journal
- Vaccines
- Published
- 2024-10-17
- DOI
- https://doi.org/10.3390/vaccines12101182
- Citations
- 1
- Primary Topic
- Probiotics and Fermented Foods
- Type
- article
- Field-Weighted Citation Impact
- 0.35
Funders
- National Natural Science Foundation of China