Suppression of virulence factors of uropathogenic Escherichia coli by Trans-resveratrol and design of nanoemulgel
The study proves the effective role of t-RSV as an antivirulence agent against clinical UPEC isolates in vitro and develops a stable t-RSV-nanoemulgel formulation to be assessed in vivo. The promising antibacterial and antivirulence properties of t-RSV place this natural compound to be a better alternative in the treatment of persistent UTIs.
Authors
- Abeer Ahmed Kassem (ORCID: https://orcid.org/0000-0002-1012-5056)
- Mona A. Moustafa (ORCID: https://orcid.org/0009-0009-0302-0107)
- Areej M. El‐Mahdy (ORCID: https://orcid.org/0000-0002-8809-5491)
- Dalia Saad ElFeky (ORCID: https://orcid.org/0000-0003-3633-3977)
- Hanan Assiri
Institutions
- Princess Nourah bint Abdulrahman University (SA)
- Cairo University (EG)
- Pharos University in Alexandria (EG)
- Mansoura University (EG)
Publication Details
- Journal
- BMC Microbiology
- Published
- 2024-10-17
- DOI
- https://doi.org/10.1186/s12866-024-03538-4
- Citations
- 4
- Primary Topic
- Escherichia coli research studies
- Type
- article
- Field-Weighted Citation Impact
- 2.47
Funders
- Cairo University
- Science and Technology Development Fund
- Princess Nourah Bint Abdulrahman University