Detection, Patterns, and Outcomes of Recurrent HPV-Positive Oropharyngeal Squamous Cell Carcinoma

In this cohort study, 10.1% of patients experienced true HPV-positive OPSCC disease recurrence, with most incidences of DM occurring in the lung and brain. Disease recurrence was identified primarily through symptomatic change, suggesting that further research may be needed to understand the optimal surveillance strategies after definitive treatment.

Authors

Catherine Brophy
Sarah G. Wilkins (ORCID: https://orcid.org/0000-0001-7060-6823)
Saral Mehra (ORCID: https://orcid.org/0000-0003-3109-7987)
Conrad Safranek (ORCID: https://orcid.org/0000-0003-1985-9432)
Hemali P. Shah (ORCID: https://orcid.org/0000-0001-6788-0979)
Rema Shah

Institutions

Yale University (US)

Publication Details

Journal: JAMA Otolaryngology–Head & Neck Surgery
Published: 2024-10-17
DOI: https://doi.org/10.1001/jamaoto.2024.3237
Citations: 4
Primary Topic: Head and Neck Cancer Studies
Type: article
Field-Weighted Citation Impact: 2.32

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article

Detection, Patterns, and Outcomes of Recurrent HPV-Positive Oropharyngeal Squamous Cell Carcinoma

Catherine Brophy, Sarah G. Wilkins, Saral Mehra, Conrad Safranek et al.

Oct 17, 2024

4 citations

JAMA Otolaryngology–Head & Neck Surgery

Head and Neck Cancer Studies

2.32

article

Detection, Patterns, and Outcomes of Recurrent HPV-Positive Oropharyngeal Squamous Cell Carcinoma

Catherine Brophy, Sarah G. Wilkins, Saral Mehra, Conrad Safranek, Hemali P. Shah, Rema Shah

October 17, 2024article en

4 citations

Abstract

In this cohort study, 10.1% of patients experienced true HPV-positive OPSCC disease recurrence, with most incidences of DM occurring in the lung and brain. Disease recurrence was identified primarily through symptomatic change, suggesting that further research may be needed to understand the optimal surveillance strategies after definitive treatment.

JAMA Otolaryngology–Head & Neck SurgeryVol. 150(12)

Yale University (US)

Good health and well-being

Openalex Percentile: Top 11%

Head and Neck Cancer Studies

2.32

DOI Open Access PDF OpenAlex

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Detection, Patterns, and Outcomes of Recurrent HPV-Positive Oropharyngeal Squamous Cell Carcinoma — Catherine Brophy, Sarah G. Wilkins, et al. · JAMA Otolaryngology–Head & Neck Surgery (2024) | TGRS Research Map | TGRS