Systemic Inflammation is Associated with Myocardial Fibrosis in Patients with Obstructive Hypertrophic Cardiomyopathy
Higher levels of IL-2 and TNF-α were associated with increased histopathological interstitial MF in patients with HCM. Given the gradual progression of MF in HCM, initiating anti-inflammatory treatment in the early stages may delay its progression.
Authors
- Xinxin Zheng (ORCID: https://orcid.org/0000-0001-5319-9461)
- Manyun Huang
- Changpeng Song (ORCID: https://orcid.org/0000-0002-1328-7544)
- Xiaohong Huang (ORCID: https://orcid.org/0000-0001-9283-021X)
- Jian Zhang (ORCID: https://orcid.org/0000-0001-7217-0111)
- Shuiyun Wang (ORCID: https://orcid.org/0000-0003-2960-8282)
- Xinli Guo
- Changrong Nie
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking University (CN)
- Shanghai East Hospital (CN)
- Peking University First Hospital (CN)
- Fu Wai Hospital (CN)
Publication Details
- Journal
- ESC Heart Failure
- Published
- 2024-10-17
- DOI
- https://doi.org/10.1002/ehf2.15109
- Citations
- 9
- Primary Topic
- Cardiomyopathy and Myosin Studies
- Type
- article
- Field-Weighted Citation Impact
- 3.62