role of the ketogenic diet in the treatment of epilepsy

Introduction: Epilepsy is a prevalent neurological condition that continues to pose therapeutic challenges. Despite the availability of various antiepileptic medications, up to one-third of patients still experience insufficient control of their seizures. One approach to managing epilepsy, particularly in drug-resistant cases, is the ketogenic diet. This diet, along with its variations, has shown effectiveness in reducing seizures across all age groups, with additional improvements in behavior. However, despite numerous studies, the exact mechanisms behind its therapeutic effects and potential risks to the body remain unclear. This review of the current literature outlines the fundamental principles and variations of the ketogenic diet, evaluates its safety and effectiveness in treating epilepsy, and explores the possible mechanisms underlying its success. Materials and methods: This article is based on the literature found in the PubMed database with the use of keywords like: "drug resistance epilepsy", "ketogenic diet", "epilepsy treatment". Conclusion: The ketogenic diet is an effective treatment for epilepsy, especially drug-resistant forms. It reduces the number of seizures and it also has a positive effect on patients' sleep and cognitive functions. Despite many years of using the diet and observing its effects we still do not fully understand its mechanisms of action.

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Publication Details

Journal
Quality in Sport
Published
2024-10-17
DOI
https://doi.org/10.12775/qs.2024.26.55234
Primary Topic
Diet and metabolism studies
Type
article
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article

role of the ketogenic diet in the treatment of epilepsy

Paweł Miłkowski, Marta Głąbień, Zofia Jakubczak, Maria Weronika Zimniak et al.
Quality in Sport
Diet and metabolism studies
article

role of the ketogenic diet in the treatment of epilepsy

Paweł Miłkowski, Marta Głąbień, Zofia Jakubczak, Maria Weronika Zimniak, Patryk Śliwiak, Karolina Kusiak, Anna Kuśnierz, Daria Aleksandrowicz, Olga Wieczorek, Aneta Kondratowicz
article en

Abstract

Introduction: Epilepsy is a prevalent neurological condition that continues to pose therapeutic challenges. Despite the availability of various antiepileptic medications, up to one-third of patients still experience insufficient control of their seizures. One approach to managing epilepsy, particularly in drug-resistant cases, is the ketogenic diet. This diet, along with its variations, has shown effectiveness in reducing seizures across all age groups, with additional improvements in behavior. However, despite numerous studies, the exact mechanisms behind its therapeutic effects and potential risks to the body remain unclear. This review of the current literature outlines the fundamental principles and variations of the ketogenic diet, evaluates its safety and effectiveness in treating epilepsy, and explores the possible mechanisms underlying its success. Materials and methods: This article is based on the literature found in the PubMed database with the use of keywords like: "drug resistance epilepsy", "ketogenic diet", "epilepsy treatment". Conclusion: The ketogenic diet is an effective treatment for epilepsy, especially drug-resistant forms. It reduces the number of seizures and it also has a positive effect on patients' sleep and cognitive functions. Despite many years of using the diet and observing its effects we still do not fully understand its mechanisms of action.

Quality in SportVol. 26
Copernicus Memorial Hospital (PL), Medical University of Lodz (PL), Central Clinical Hospital (PL)
Good health and well-being
Openalex Percentile: Top 75%
Diet and metabolism studies
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role of the ketogenic diet in the treatment of epilepsy — Paweł Miłkowski, Marta Głąbień, et al. · Quality in Sport (2024) | TGRS Research Map | TGRS