Image Stitching of Low-Resolution Retinography Using Fundus Blur Filter and Homography Convolutional Neural Network

Great advances in stitching high-quality retinal images have been made in recent years. On the other hand, very few studies have been carried out on low-resolution retinal imaging. This work investigates the challenges of low-resolution retinal images obtained by the D-EYE smartphone-based fundus camera. The proposed method uses homography estimation to register and stitch low-quality retinal images into a cohesive mosaic. First, a Siamese neural network extracts features from a pair of images, after which the correlation of their feature maps is computed. This correlation map is fed through four independent CNNs to estimate the homography parameters, each specializing in different corner coordinates. Our model was trained on a synthetic dataset generated from the Microsoft Common Objects in Context (MSCOCO) dataset; this work added an important data augmentation phase to improve the quality of the model. Then, the same is evaluated on the FIRE retina and D-EYE datasets for performance measurement using the Peak Signal-to-Noise Ratio (PSNR) and Structural Similarity Index (SSIM). The obtained results are promising: the average PSNR was 26.14 dB, with an SSIM of 0.96 on the D-EYE dataset. Compared to the method that uses a single neural network for homography calculations, our approach improves the PSNR by 7.96 dB and achieves a 7.86% higher SSIM score.