Unveiling Eco‐Friendly Reverse Micelle Systems: Dimethyl Carbonate as a Novel Biocompatible Solvent

In this study, we systematically explored the characteristics of dimethyl carbonate (DMC)/sodium 1,4-bis-2-ethylhexylsulfosuccinate (AOT) reverse micelles (RMs) in the presence of water using dynamic light scattering (DLS), proton nuclear magnetic resonance (¹H NMR), and molecular probes. DMC, a biocompatible solvent, enables the formulation of AOT RMs without the need for a co-surfactant. DLS revealed that as the water content increased, the droplet sizes grew larger. ¹H NMR studies indicated that at low water content, water molecules interacted with DMC via hydrogen bonding. This interaction promoted the penetration of DMC toward the interface, affecting the solvation of AOT's sulfonate group. At higher water content, a competition for hydrogen bonding emerged between water-water and water-surfactant molecules, leading to distinct interfacial properties, as evidenced by molecular probes. The critical micellar concentration for DMC/AOT/water RMs was 7×10^-3 M, similar to RMs formed with other biocompatible solvents. The presence of water facilitated the solvation of the surfactant's polar regions, promoting the RMs formation. The polarity of this system was measured using the E_T(30) value. This novel micellar system holds significant potential in various fields, including catalysis, nanomaterials, and green chemistry.