Nociceptive TRP channels function as molecular target for several antifungal drugs

These results suggest that topical antifungal-induced pain and irritation are attributable to the activation of nociceptive TRPA1 and/or TRPV1 channel/s. Consequently, caution should be exercised in the use of topical antifungals with symptoms of pain.

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Publication Details

Journal
Fundamental and Clinical Pharmacology
Published
2024-10-17
DOI
https://doi.org/10.1111/fcp.13039
Citations
2
Primary Topic
Ion Channels and Receptors
Type
article
Field-Weighted Citation Impact
0.72

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article

Nociceptive TRP channels function as molecular target for several antifungal drugs

Kenji Takahashi, Miho Hashimoto, Toshio Ohta, Shota Okabe
2 citations
Fundamental and Clinical Pharmacology
Ion Channels and Receptors
0.72
article

Nociceptive TRP channels function as molecular target for several antifungal drugs

Kenji Takahashi, Miho Hashimoto, Toshio Ohta, Shota Okabe
article en
2 citations

Abstract

These results suggest that topical antifungal-induced pain and irritation are attributable to the activation of nociceptive TRPA1 and/or TRPV1 channel/s. Consequently, caution should be exercised in the use of topical antifungals with symptoms of pain.

Fundamental and Clinical PharmacologyVol. 38(6)
Tottori University (JP)
Japan Society for the Promotion of Science
Openalex Percentile: Top 30%
Ion Channels and Receptors
0.72
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