Comparative study of pathogen detection methods for central nervous system infections: laboratory testing of tuberculous meningitis
This study highlights the high sensitivity of mNGS, comparable to GeneXpert and MTB culture. The combined methods are cost-effective and straightforward, and can partially substitute for mNGS, offering valuable alternatives for TBM diagnosis and providing insights into multiple diagnostic strategies in clinical practice.
Authors
- Xujie Zhu
- Wanzhen Xu
- Guobao Li (ORCID: https://orcid.org/0000-0003-3061-193X)
- Dapeng Li
- Lanlan Wei (ORCID: https://orcid.org/0000-0002-6060-4303)
- Zengchen Liu (ORCID: https://orcid.org/0009-0000-4677-2127)
- Shengkun Zhang
- Yijie Wang (ORCID: https://orcid.org/0000-0002-2681-0138)
- Ming Chu
- Dian Wang (ORCID: https://orcid.org/0009-0009-0015-0651)
- Yufeng Tang
- Fangjia Tong
Institutions
- Southern University of Science and Technology (CN)
- Shantou University (CN)
- Shenzhen Maternity and Child Healthcare Hospital (CN)
- Shenzhen Third People’s Hospital (CN)
Publication Details
- Journal
- BMC Infectious Diseases
- Published
- 2024-10-17
- DOI
- https://doi.org/10.1186/s12879-024-10037-4
- Citations
- 3
- Primary Topic
- Infectious Diseases and Tuberculosis
- Type
- article
- Field-Weighted Citation Impact
- 1.72
Funders
- Guangdong Science and Technology Department
- Shenzhen University