Transmitted drug resistance and molecular transmission network among treatment-naive HIV-1 patients in Wenzhou, China, 2020–2023
While TDR prevalence in Wenzhou remained lower than in other Chinese regions, an upward trend was observed. Most resistant individuals were in transmission clusters, predominantly middle-aged and elderly. NNRTI resistance was severe and concentrated in efavirenz, nevirapine, and rilpivirine. Enhanced HIV surveillance and wider free antiretroviral options are crucial to control drug-resistant HIV spread in Wenzhou.
Authors
- Binbin Lv
- Mingyuan Zhou (ORCID: https://orcid.org/0000-0002-4253-2780)
- Bao‐Chang Sun (ORCID: https://orcid.org/0000-0002-3435-1250)
- Han Tang (ORCID: https://orcid.org/0000-0001-9783-9416)
- Tianran Zhang (ORCID: https://orcid.org/0009-0005-7850-3243)
- Weilong Wang (ORCID: https://orcid.org/0000-0001-6280-8118)
- Hui Ye (ORCID: https://orcid.org/0000-0001-5438-5952)
- Haiyang Dai (ORCID: https://orcid.org/0000-0003-0366-7751)
- Wenxue Hu (ORCID: https://orcid.org/0000-0003-4181-5719)
- Weiqin Wang
- Hong Yan Dou
Institutions
- Wenzhou Central Hospital (CN)
- Wenzhou Municipal Sci-Tech Bureau (CN)
- Wenzhou Institute of Technology Testing & Calibration (CN)
Publication Details
- Journal
- Virology Journal
- Published
- 2024-10-17
- DOI
- https://doi.org/10.1186/s12985-024-02528-2
- Citations
- 4
- Primary Topic
- HIV/AIDS drug development and treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.56
Funders
- Wenzhou Municipal Science and Technology Bureau