Encapsulation nanoarchitectonics of glabridin with sophorolipid micelles for addressing biofilm hazards via extracellular polymeric substance permeation and srtA gene suppression
GLA@SOL/EYL utilizes the nanoparticle effect to penetrate biofilms and deliver antimicrobial GLA. The SOL disperses the biofilm matrix while GLA is released to kill S. aureus, preventing bacterial dissemination and colonization. Thus, GLA@SOL/EYL presents an innovative strategy for effectively eradicating S. aureus biofilms and preventing new hazards in a one-step approach.
Authors
- Shiyu Lin (ORCID: https://orcid.org/0000-0003-1433-3175)
- Funeng Xu (ORCID: https://orcid.org/0000-0002-0377-9246)
- Gang Shu (ORCID: https://orcid.org/0000-0002-0610-9635)
- Guangneng Peng (ORCID: https://orcid.org/0000-0002-9898-5754)
- Haohuan Li (ORCID: https://orcid.org/0000-0003-3215-5181)
- Li Zhang (ORCID: https://orcid.org/0009-0004-8361-8128)
- Xiaojuan Li (ORCID: https://orcid.org/0000-0002-2668-3044)
- Wei Zhang (ORCID: https://orcid.org/0000-0002-1912-8077)
- Juchun Lin (ORCID: https://orcid.org/0000-0001-8563-9126)
- Hualin Fu
Institutions
- Sichuan Agricultural University (CN)
- Sichuan Academy of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Ecotoxicology and Environmental Safety
- Published
- 2024-10-17
- DOI
- https://doi.org/10.1016/j.ecoenv.2024.117150
- Citations
- 1
- Primary Topic
- Biochemical and Structural Characterization
- Type
- article
- Field-Weighted Citation Impact
- 0.23