Prognostic significance and biological implications of SM-like genes in mantle cell lymphoma
The LSM.index demonstrates potential as a prognostic marker for survival in patients with MCL. Elevated expression of LSM genes, particularly LSM1 and LSM8, may be linked to poor survival outcomes through their involvement in cell division and RNA splicing pathways. These findings suggest that LSM genes may contribute to the aggressive behavior of MCL and represent potential targets for therapeutic interventions.
Authors
- Yan Liu (ORCID: https://orcid.org/0000-0002-8314-985X)
- Wei Zhang (ORCID: https://orcid.org/0000-0002-6190-3129)
- Xin Huang (ORCID: https://orcid.org/0000-0002-0413-3340)
- Xue He (ORCID: https://orcid.org/0000-0003-4448-5399)
- Changjian Yan
- Mingxia Zhu (ORCID: https://orcid.org/0000-0002-3925-3115)
- Xiaoliang Yuan (ORCID: https://orcid.org/0000-0003-2479-0361)
- Shaoxiang Li (ORCID: https://orcid.org/0000-0001-7127-5421)
- Zimu Zhou
- Wei Fu
- Jing Wang (ORCID: https://orcid.org/0000-0001-9981-5530)
- Weijia Wang (ORCID: https://orcid.org/0000-0003-2162-9177)
- Jing Hu (ORCID: https://orcid.org/0000-0001-7604-6732)
- Yaru Yang (ORCID: https://orcid.org/0000-0001-5750-0581)
- Xiaoni Liu (ORCID: https://orcid.org/0000-0003-1101-4013)
- Weilong Zhang (ORCID: https://orcid.org/0009-0009-4052-200X)
- Chaoling Wu (ORCID: https://orcid.org/0000-0002-4517-0818)
- Yuansheng Lin (ORCID: https://orcid.org/0009-0007-6178-5154)
- Hongmei Jing (ORCID: https://orcid.org/0000-0002-1795-5650)
- Gehong Dong
- Ping Yang (ORCID: https://orcid.org/0009-0003-3987-7467)
Institutions
- Fujian Medical University (CN)
- Jiujiang University (CN)
- Nanchang University (CN)
- Capital Medical University (CN)
- Dalian Medical University (CN)
- Peking University (CN)
- Beijing Tian Tan Hospital (CN)
- Second Affiliated Hospital of Chongqing Medical University (CN)
- Gannan Medical University (CN)
- Suzhou Municipal Hospital (CN)
- First Affiliated Hospital of Gannan Medical University (CN)
- Second Affiliated Hospital of Fujian Medical University (CN)
- Peking University Third Hospital (CN)
- First Affiliated Hospital of Nanchang University (CN)
- Chongqing Medical University (CN)
- Nanjing University (CN)
Publication Details
- Journal
- Blood Research
- Published
- 2024-10-17
- DOI
- https://doi.org/10.1007/s44313-024-00037-3
- Primary Topic
- RNA Research and Splicing
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Peking University
- Peking University Third Hospital
- China Health Promotion Foundation
- Health Commission of Jiangxi Province
- Wu Jieping Medical Foundation
- Interdisciplinary Medicine Seed Fund of Peking University