Production of mRNA lipid nanoparticles using advanced crossflow micromixing

We confirm the applicability of stainless-steel crossflow membrane micromixing for the entire spectrum of mRNA-LNP production, ranging from initial discovery volumes to GMP-production scale.

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Publication Details

Journal
Journal of Pharmacy and Pharmacology
Published
2024-10-09
DOI
https://doi.org/10.1093/jpp/rgae122
Citations
16
Primary Topic
RNA Interference and Gene Delivery
Type
article
Field-Weighted Citation Impact
3.74
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article

Production of mRNA lipid nanoparticles using advanced crossflow micromixing

Yvonne Perrie, Muattaz Hussain, Burcu Binici, Louisa O’Connor
16 citations
Journal of Pharmacy and Pharmacology
RNA Interference and Gene Delivery
3.74
article

Production of mRNA lipid nanoparticles using advanced crossflow micromixing

Yvonne Perrie, Muattaz Hussain, Burcu Binici, Louisa O’Connor
article en
16 citations

Abstract

We confirm the applicability of stainless-steel crossflow membrane micromixing for the entire spectrum of mRNA-LNP production, ranging from initial discovery volumes to GMP-production scale.

Journal of Pharmacy and PharmacologyVol. 76(12)
University of Strathclyde (GB)
Openalex Percentile: Top 6%
RNA Interference and Gene Delivery
3.74
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Production of mRNA lipid nanoparticles using advanced crossflow micromixing — Yvonne Perrie, Muattaz Hussain, et al. · Journal of Pharmacy and Pharmacology (2024) | TGRS Research Map | TGRS