Associations Between Loneliness, Epigenetic Aging, and Multimorbidity Through Older Adulthood
These results suggest that the impact of loneliness on multimorbidity may, in part, operate through DNA methylation. The specific intermediary, physiological mechanisms that are involved will require further research, but EAA measures like GrimAge are promising in helping to understand the health impacts of loneliness.
Authors
- Steve W. Cole (ORCID: https://orcid.org/0000-0002-7168-8039)
- Colin D. Freilich (ORCID: https://orcid.org/0000-0002-6183-7520)
- Kristian E. Markon (ORCID: https://orcid.org/0000-0002-7230-9694)
- Frank D. Mann (ORCID: https://orcid.org/0000-0002-5450-0620)
- Robert F. Krueger
Institutions
- University of Minnesota (US)
- University of California, Los Angeles (US)
- Stony Brook School (US)
- Twin Cities Orthopedics (US)
- Stony Brook University (US)
Publication Details
- Journal
- The Journals of Gerontology Series B
- Published
- 2024-10-17
- DOI
- https://doi.org/10.1093/geronb/gbae169
- Citations
- 12
- Primary Topic
- Health disparities and outcomes
- Type
- article
- Field-Weighted Citation Impact
- 6.34
Funders
- U.S. Social Security Administration
- National Institute on Aging