[Acquired hemophilia - quick diagnosis and treatment can significantly reduce the risk of mortality].

This case report of a 73-year-old male with bleedings provides insights into the clinical characteristics, diagnosis och treatment of acquired hemophilia A. It's a dangerous non-hereditary bleeding disorder caused by autoantibodies against coagulation factor VIII, often linked with other autoimmune diseases or malignancies, but it is also often idiopathic. The diagnosis remains a challenge due to its rarity and non-specific symtoms, but should be considered in unexplained bleeding cases with prolonged activated partial thromboplastin time (APTT). Quick diagnosis and treatment can significantly reduce the risk of serious complications and mortality. The long-term prognosis usually depends on the presence of any underlying disease.

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PubMed
Published
2024-10-09
Primary Topic
Hemophilia Treatment and Research
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article
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article

[Acquired hemophilia - quick diagnosis and treatment can significantly reduce the risk of mortality].

Jouni K. Johansson, Mårten Söderberg
PubMed
Hemophilia Treatment and Research
article

[Acquired hemophilia - quick diagnosis and treatment can significantly reduce the risk of mortality].

Jouni K. Johansson, Mårten Söderberg
article en

Abstract

This case report of a 73-year-old male with bleedings provides insights into the clinical characteristics, diagnosis och treatment of acquired hemophilia A. It's a dangerous non-hereditary bleeding disorder caused by autoantibodies against coagulation factor VIII, often linked with other autoimmune diseases or malignancies, but it is also often idiopathic. The diagnosis remains a challenge due to its rarity and non-specific symtoms, but should be considered in unexplained bleeding cases with prolonged activated partial thromboplastin time (APTT). Quick diagnosis and treatment can significantly reduce the risk of serious complications and mortality. The long-term prognosis usually depends on the presence of any underlying disease.

PubMedVol. 121
Stockholm South General Hospital (SE), Drottning Silvias barn- och ungdomssjukhus (SE)
Openalex Percentile: Top 71%
Hemophilia Treatment and Research
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[Acquired hemophilia - quick diagnosis and treatment can significantly reduce the risk of mortality]. — Jouni K. Johansson, Mårten Söderberg · PubMed (2024) | TGRS Research Map | TGRS