Interleukin-1 receptor-dependent and -independent caspase-1 activity in retinal cells mediated by receptor interacting protein 2
We conclude that any intervention in caspase-1/IL-1β/IL-1R1 feedback signaling presents novel therapeutic options for the treatment of diabetic retinopathy.
Authors
- Brandon Coughlin
- Brett Thomas Trombley
- Barbara Christian
- Susanne Mohr
Institutions
- Michigan State University (US)
Publication Details
- Journal
- Frontiers in Cell and Developmental Biology
- Published
- 2024-10-16
- DOI
- https://doi.org/10.3389/fcell.2024.1467799
- Citations
- 3
- Primary Topic
- Retinal Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.62
Funders
- National Institutes of Health