Obesity-related drug transporter expression alterations in human liver and kidneys
The observed alterations may be reflected by the differences in drug PK between lean and obese populations. However, these findings need further evaluation through the proteomic and functional study of these transporters in this patient population.
Authors
- Luigi Brunetti (ORCID: https://orcid.org/0000-0003-0565-6167)
- Christine N. Yohn (ORCID: https://orcid.org/0000-0002-9619-7500)
- Katarzyna Kosicka (ORCID: https://orcid.org/0000-0003-3551-4784)
- Leonid Kagan (ORCID: https://orcid.org/0000-0003-3863-4757)
- Aleksandra Romaniuk-Drapała (ORCID: https://orcid.org/0000-0002-3922-8729)
- Yi-Hua Sheng
Institutions
- Rutgers, The State University of New Jersey (US)
- Poznan University of Medical Sciences (PL)
- Environmental and Occupational Health Sciences Institute (US)
Publication Details
- Journal
- Pharmacological Reports
- Published
- 2024-10-16
- DOI
- https://doi.org/10.1007/s43440-024-00665-7
- Citations
- 1
- Primary Topic
- Drug Transport and Resistance Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.28
Funders
- Kosciuszko Foundation
- National Institutes of Health
- National Institute of General Medical Sciences