Fatty acid metabolism prognostic signature predicts tumor immune microenvironment and immunotherapy, and identifies tumorigenic role of MOGAT2 in lung adenocarcinoma
This FAM-related gene signature provides a valuable tool for prognostic stratification and monitoring of TIME and immunotherapy responses in LUAD. MOGAT2 is identified as a potential anti-tumor regulator, offering new insights into its role in LUAD pathogenesis.
Authors
- Denggang Fu (ORCID: https://orcid.org/0000-0001-7274-033X)
- Xin Wang (ORCID: https://orcid.org/0000-0002-5122-2418)
- Jueping Feng (ORCID: https://orcid.org/0000-0002-5334-6860)
- Fanfan Zeng (ORCID: https://orcid.org/0000-0002-1400-4745)
- Biyu Zhang (ORCID: https://orcid.org/0000-0003-2437-8043)
- Wenyan Fan
Institutions
- Jiujiang University (CN)
- Nanchang University (CN)
- Medical University of South Carolina (US)
- Wuhan Puai Hospital (CN)
- Wuhan Institute of Technology (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2024-10-16
- DOI
- https://doi.org/10.3389/fimmu.2024.1456719
- Citations
- 13
- Primary Topic
- Cancer, Lipids, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 3.71
Funders
- Natural Science Foundation of Jiangxi Province