Inhibition of angiogenesis and regenerative lung growth in Lepob/ob mice through adiponectin-VEGF/VEGFR2 signaling
These findings suggest that obesity impairs lung vascular and alveolar regeneration and adiponectin is one of the key factors to improve lung regeneration in obese people.
Authors
- Priscilla Kyi
- Mario Gasparri
- Akiko Mammoto (ORCID: https://orcid.org/0000-0003-3448-7331)
- Mrudula Joshi (ORCID: https://orcid.org/0000-0001-7312-351X)
- Tadanori Mammoto (ORCID: https://orcid.org/0009-0002-0985-0856)
- Marian G.W. Scheer (ORCID: https://orcid.org/0009-0003-1359-9833)
- Tendai Hunyenyiwa
Institutions
- Medical College of Wisconsin (US)
Publication Details
- Journal
- Frontiers in Cardiovascular Medicine
- Published
- 2024-10-16
- DOI
- https://doi.org/10.3389/fcvm.2024.1491971
- Citations
- 4
- Primary Topic
- Biomarkers in Disease Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.96