Family Malvaceae: a potential source of secondary metabolites with chemopreventive and anticancer activities supported with in silico pharmacokinetic and pharmacodynamic profiles
Overall, the current study presents helpful insights into the pharmacokinetic and pharmacodynamic properties of the reported cytotoxic metabolites belonging to family Malvaceae members. The molecular docking and dynamic simulations results intensify the roles of secondary metabolites from medicinal plants in fighting cancer.
Authors
- Salma Sameh
- Abdel Nasser B. Singab (ORCID: https://orcid.org/0000-0001-7445-963X)
- Rola M. Labib (ORCID: https://orcid.org/0000-0002-7531-4552)
- Hsueh‐Wei Chang (ORCID: https://orcid.org/0000-0003-0068-2366)
- Fang‐Rong Chang (ORCID: https://orcid.org/0000-0003-2549-4193)
- Szu‐Yin Yu (ORCID: https://orcid.org/0000-0002-5138-5540)
- Ahmed M. Elissawy (ORCID: https://orcid.org/0000-0003-1584-7653)
- Shyh‐Chyun Yang (ORCID: https://orcid.org/0000-0002-3999-3471)
- Eman Al‐Sayed (ORCID: https://orcid.org/0000-0001-7869-2009)
Institutions
- Ain Shams University (EG)
- Kaohsiung Medical University (TW)
- Kaohsiung Medical University Chung-Ho Memorial Hospital (TW)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2024-10-16
- DOI
- https://doi.org/10.3389/fphar.2024.1465055
- Citations
- 6
- Primary Topic
- Computational Drug Discovery Methods
- Type
- article
- Field-Weighted Citation Impact
- 2.17