Application of Iodine-Amine Oxidation Approach in the Synthesis of Various N-Alkyl Phosphoramidate Oligonucleotide Derivatives
The obtained data indicates that the oxidative amination approach can be a promising tool for preparing various oligonucleotide derivatives during solid-phase synthesis without the use of specialized phosphoramidite monomers.
Authors
- Д. В. Пышный (ORCID: https://orcid.org/0000-0002-2587-3719)
- Maxim S. Kupryushkin (ORCID: https://orcid.org/0000-0002-2300-7809)
- Mikhail D. Nekrasov (ORCID: https://orcid.org/0000-0002-6510-499X)
Institutions
- Institute of Chemical Biology and Fundamental Medicine (RU)
- Siberian Branch of the Russian Academy of Sciences (RU)
Publication Details
- Journal
- Medicinal Chemistry
- Published
- 2024-10-16
- DOI
- https://doi.org/10.2174/0115734064325532241002105426
- Citations
- 1
- Primary Topic
- Synthesis and Characterization of Heterocyclic Compounds
- Type
- article
- Field-Weighted Citation Impact
- 0.25