Heterogeneous Origins of Calcium Homeostasis Disorders Arising From 5 Heterozygous Calcium-Sensing Receptor Variants
While the molecular phenotypes exhibited by the 5 CaSR variants concord with the clinical phenotypes in individuals harboring them, CASR variant-induced calcium homeostasis disorders clearly arise from diverse molecular origins, and the effectiveness of calcimimetics in these disorders could differ depending on the specific variants.
Authors
- Martin Blomberg Jensen (ORCID: https://orcid.org/0000-0003-3800-4253)
- Jesper Mosolff Mathiesen (ORCID: https://orcid.org/0000-0003-4251-4416)
- Sabrina N. Rahman
- Ida Marie Boisen (ORCID: https://orcid.org/0000-0003-2401-2877)
- Nadia Nicholine Poulsen (ORCID: https://orcid.org/0000-0002-0625-1770)
- Hans Bräuner‐Osborne (ORCID: https://orcid.org/0000-0001-9495-7388)
- Du Wei (ORCID: https://orcid.org/0000-0003-1215-2223)
- Anders A. Jensen (ORCID: https://orcid.org/0000-0002-7927-5052)
Institutions
- University of Copenhagen (DK)
- Novo Nordisk Foundation (DK)
Publication Details
- Journal
- The Journal of Clinical Endocrinology & Metabolism
- Published
- 2024-10-16
- DOI
- https://doi.org/10.1210/clinem/dgae735
- Primary Topic
- Parathyroid Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Lundbeckfonden
- China Scholarship Council
- Novo Nordisk Fonden
- Danmarks Frie Forskningsfond