Therapeutic Effects of Crocin Nanoparticles Alone or in Combination with Doxorubicin against Hepatocellular Carcinoma In vitro
Although more in vivo studies in animal models are required to corroborate these results, our findings suggest that CRO-NPs can be a potential new anticancer agent for hepatocellular carcinoma. Moreover, they have a synergistic effect with DOX against HepG2 cells and mitigate the toxicity of DOX on normal WI38 cells.
Authors
- Tarek M. Mohamed (ORCID: https://orcid.org/0000-0002-4015-7542)
- Mona Elwan (ORCID: https://orcid.org/0000-0002-3214-4549)
- Doha M. Beltagy
- Ahmed Massoud
- Noha S. Basuony
Institutions
- Damanhour University (EG)
- Tanta University (EG)
Publication Details
- Journal
- Anti-Cancer Agents in Medicinal Chemistry
- Published
- 2024-10-16
- DOI
- https://doi.org/10.2174/0118715206327654240823074318
- Citations
- 2
- Primary Topic
- Saffron Plant Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.57