N6-methyladenosine-modified circCDK14 promotes ossification of the ligamentum flavum via epigenetic modulation by targeting AFF4
The m6A-modified CircCDK14 binding to miR-93-5p played an important role in the osteogenesis of LF cells by targeting AFF4, providing a promising therapeutic target for OLF.
Authors
- Weishi Li (ORCID: https://orcid.org/0000-0001-9512-5436)
- Jialiang Lin (ORCID: https://orcid.org/0000-0001-9067-6423)
- Yongzhao Zhao (ORCID: https://orcid.org/0000-0002-3032-4765)
- Shuai Jiang (ORCID: https://orcid.org/0000-0002-9737-9744)
- Longting Chen (ORCID: https://orcid.org/0000-0002-6647-305X)
- Qian Xiang (ORCID: https://orcid.org/0000-0002-8245-2611)
Institutions
- Peking University (CN)
- Beijing Forestry University (CN)
- Ministry of Education (SA)
- Peking University Third Hospital (CN)
Publication Details
- Journal
- Cellular and Molecular Life Sciences
- Published
- 2024-10-16
- DOI
- https://doi.org/10.1007/s00018-024-05460-4
- Citations
- 6
- Primary Topic
- Magnesium Alloys: Properties and Applications
- Type
- article
- Field-Weighted Citation Impact
- 1.04
Funders
- National Natural Science Foundation of China