Incremental Prognostic Value of a Coronary Heart Disease Polygenic Risk Score in Type 2 Diabetes
The addition of a CHD PRS to clinical assessment improved MACE prediction in T2D individuals without prior cardiovascular disease, particularly in those at low clinical risk.
Authors
- Alex S. F. Doney (ORCID: https://orcid.org/0000-0002-6210-5620)
- Ify Mordi (ORCID: https://orcid.org/0000-0002-2686-729X)
- Gittu George (ORCID: https://orcid.org/0000-0002-1312-8463)
- Rory J. McCrimmon (ORCID: https://orcid.org/0000-0002-3957-1981)
- Chim C. Lang (ORCID: https://orcid.org/0000-0002-4530-3078)
- Ewan R. Pearson (ORCID: https://orcid.org/0000-0001-9237-8585)
- Ivy Li (ORCID: https://orcid.org/0009-0003-9064-0801)
Institutions
- University of Dundee (GB)
Publication Details
- Journal
- Diabetes Care
- Published
- 2024-10-16
- DOI
- https://doi.org/10.2337/dc24-1489
- Citations
- 2
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 1.10
Funders
- National Institute for Health and Care Research
- British Heart Foundation
- Chief Scientist Office
- Medical Research Council