Formulation and Evaluation of Controlled Release Tablet Using Thyme and Rosemary for Osteoporosis

Osteoporosis is a common public health problem which currently affected millions of people worldwide. Osteoporosis is mainly associated with Ovarian hormone deficiency following menopause is till now a most common reason of age-related bone loss. There are tablets that are available in the market, which shows the side effect such as nausea, heart burn, gastric problem after the continuous use of medicine. These side effects led to the avoidance of such medicine. Using herbal plant such as thyme and rosemary as an alternative of those drug will help to reduce these effects. Hence, selected to develop a Controlled Release Tablet of Rosemary and Thyme. Tablet is the most popular among all dosage forms existing today because of its convenience of self-administration, compactness and easy manufacturing. Developing the tablet using thyme and rosemary in the form of controlled release drug will help to prolonged the effect of the medicine. As precision of dosing, to improve the bioavailability of the drug and to maintain the constant level of drug in the plasma become important to provide the long-term effect to the patient. It will also provide the patience compliance as well as prolonged the effect of drug in the patient’s body.