Phase 3 Trial of Stereotactic Body Radiotherapy in Localized Prostate Cancer
Five-fraction SBRT was noninferior to control radiotherapy with respect to biochemical or clinical failure and may be an efficacious treatment option for patients with low-to-intermediate-risk localized prostate cancer as defined in this trial. (Funded by Accuray and others; PACE-B ClinicalTrials.gov number, NCT01584258.).
Authors
- Paula Wells (ORCID: https://orcid.org/0000-0002-2631-5380)
- Nicholas van As (ORCID: https://orcid.org/0000-0001-6829-8788)
- Alexander Martin (ORCID: https://orcid.org/0000-0002-5988-9911)
- Emily Williamson
- Derek Price
- Daniel Ford
- Jaymini Patel (ORCID: https://orcid.org/0000-0001-5690-8630)
- Peter Ostler (ORCID: https://orcid.org/0000-0002-6859-6723)
- John Staffurth (ORCID: https://orcid.org/0000-0002-7834-3172)
- Clare Griffin (ORCID: https://orcid.org/0000-0002-0127-4201)
- Alison Tree (ORCID: https://orcid.org/0000-0002-5033-424X)
- Stephanie Brown (ORCID: https://orcid.org/0000-0003-4473-843X)
- Stephanie Burnett
- Shaun Tolan
- Julia Pugh (ORCID: https://orcid.org/0000-0002-7853-9642)
- Emma Hall (ORCID: https://orcid.org/0000-0001-5999-5020)
- Olivia Naismith
- Philip Camilleri (ORCID: https://orcid.org/0000-0002-2677-5627)
- H. van der Voet
- Kiran Kancherla
- Georgina Manning (ORCID: https://orcid.org/0000-0003-2198-0880)
- Ian S. Dayes (ORCID: https://orcid.org/0000-0001-8550-1485)
- Andrew K. Chan (ORCID: https://orcid.org/0000-0001-6953-0120)
- William Chu (ORCID: https://orcid.org/0000-0002-9307-0184)
- John Armstrong
- J. Frew
- Andrew Loblaw
- Suneil Jain (ORCID: https://orcid.org/0000-0001-7429-4791)
Institutions
- Cancer Research UK (GB)
Publication Details
- Journal
- New England Journal of Medicine
- Published
- 2024-10-16
- DOI
- https://doi.org/10.1056/nejmoa2403365
- Citations
- 183
- Primary Topic
- Prostate Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 76.66
Funders
- Royal Marsden NHS Foundation Trust
- Accuray
- Prostate Cancer Canada
- Cancer Research UK
- National Institute for Health and Care Research