Engineered Mycobacteriophage TM4::<i>GeNL</i> Rapidly Determines Bedaquiline, Pretomanid, Linezolid, Rifampicin, and Clofazimine Sensitivity in <i>Mycobacterium tuberculosis</i> Clinical Isolates

TM4::GeNL reporter phage DST offers a rapid method to identify M. tuberculosis drug resistance, including resistance to newer tuberculosis drugs.

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Publication Details

Journal
The Journal of Infectious Diseases
Published
2024-10-16
DOI
https://doi.org/10.1093/infdis/jiae438
Citations
4
Primary Topic
Tuberculosis Research and Epidemiology
Type
article
Field-Weighted Citation Impact
1.56

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article

Engineered Mycobacteriophage TM4::GeNL Rapidly Determines Bedaquiline, Pretomanid, Linezolid, Rifampicin, and Clofazimine Sensitivity in Mycobacterium tuberculosis Clinical Isolates

William R. Jacobs, Michelle H. Larsen, Lahari Das, Donna Kohlerschmidt et al.
4 citations
The Journal of Infectious Diseases
Tuberculosis Research and Epidemiology
1.56
article

Engineered Mycobacteriophage TM4::GeNL Rapidly Determines Bedaquiline, Pretomanid, Linezolid, Rifampicin, and Clofazimine Sensitivity in Mycobacterium tuberculosis Clinical Isolates

William R. Jacobs, Michelle H. Larsen, Lahari Das, Donna Kohlerschmidt, Vincent Escuyer, Michael Berney, Amy K. Rourke, Catherine Vilchèze, Vaishnavi Mahalingam, Barry Truebody, Emmanuel Asare, Claire V. Mulholland, Rubeshan Perumal, Senamile L. Ngema, Jared S. Mackenzie, Rajagopalan Saranathan, Adrie J. C. Steyn, Max R. O’Donnell, Sashen Moodley
article en
4 citations

Abstract

TM4::GeNL reporter phage DST offers a rapid method to identify M. tuberculosis drug resistance, including resistance to newer tuberculosis drugs.

The Journal of Infectious DiseasesVol. 231(4)
South African Medical Research Council (ZA), New York State Department of Health (US), Albert Einstein College of Medicine (US), Wadsworth Center (US), Columbia University Irving Medical Center (US), Centre for the AIDS Programme of Research in South Africa (ZA), University of Alabama at Birmingham (US), Africa Health Research Institute (ZA), University of KwaZulu-Natal (ZA)
National Institutes of Health, National Institute of Allergy and Infectious Diseases
Good health and well-being
Openalex Percentile: Top 17%
Tuberculosis Research and Epidemiology
1.56
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