Cohesin RAD21 Gene Promoter Methylation in Patients with Acute Myeloid Leukemia
This is the first study which provides evidence for a possible pathogenetic role of <i>RAD21</i> promoter methylation in AML development and especially in AML with trisomy 8. Further studies of <i>RAD21</i> promoter methylation in large series of different AML genetic subgroups may contribute to the elucidation of AML pathogenesis and to the identification of new epigenetic biomarkers with diagnostic and prognostic value.
Authors
- Agapi Ioannidou
- Sophia Zachaki
- Kalliopi N. Manola
- Katerina Kakosaiou
- Marina Kalomoiraki
- Θεόδωρος Ράμπιας (ORCID: https://orcid.org/0000-0002-5460-5334)
Institutions
- National Centre of Scientific Research "Demokritos" (GR)
- Academy of Athens (GR)
Publication Details
- Journal
- Life
- Published
- 2024-10-16
- DOI
- https://doi.org/10.3390/life14101311
- Citations
- 1
- Primary Topic
- Acute Myeloid Leukemia Research
- Type
- article
- Field-Weighted Citation Impact
- 0.45