Light Chain Multiple Myeloma: A Case of Distinctive Presentations

Multiple Myeloma (MM) is a malignancy of immunoglobulin-producing plasma cells. Lambda Light Chain Multiple Myeloma (LCMM) is a less common type of MM with a more aggressive course, which presents a diagnostic challenge due to the absence of typical M-spike on screening and unspecific manifestations. This case presented an initially misdiagnosed patient, who had an uncommon light chain pattern on electrophoresis, atypical plasmocytes in bone marrow smear, particular complications and risks associated with LCMM, and a worse prognosis.

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Publication Details

Journal
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY
Published
2024-10-16
DOI
https://doi.org/10.24293/ijcpml.v31i1.2088
Primary Topic
Multiple Myeloma Research and Treatments
Type
article
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article

Light Chain Multiple Myeloma: A Case of Distinctive Presentations

Fify Henrika, Reiva Wisdharilla
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY
Multiple Myeloma Research and Treatments
article

Light Chain Multiple Myeloma: A Case of Distinctive Presentations

Fify Henrika, Reiva Wisdharilla
article en

Abstract

Multiple Myeloma (MM) is a malignancy of immunoglobulin-producing plasma cells. Lambda Light Chain Multiple Myeloma (LCMM) is a less common type of MM with a more aggressive course, which presents a diagnostic challenge due to the absence of typical M-spike on screening and unspecific manifestations. This case presented an initially misdiagnosed patient, who had an uncommon light chain pattern on electrophoresis, atypical plasmocytes in bone marrow smear, particular complications and risks associated with LCMM, and a worse prognosis.

INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORYVol. 31(1)
Rumah Sakit Umum Pusat Nasional Dr. Cipto Mangunkusumo (ID)
Good health and well-being
Openalex Percentile: Top 71%
Multiple Myeloma Research and Treatments
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