Rare-Earth-Metal-Catalyzed Regioselective Hydrosilylation of Internal Alkenes and Alkynes

Abstract A highly regioselective hydrosilylation reaction of internal alkenes was achieved by using commercially available lanthanum hexamethyldisilazane (La(HMDS)3). Notably, the Z- or E-configuration of internal alkenes has negligible influence on either the reactivity or regioselectivity. Internal alkynes could also be used, affording the mono di-hydrosilylation product in the presence of La(HMDS)3 or mono-hydrosilylation product with Y(HMDS)3 as the promoter.