Practical Consensus Guidelines on the Use of Cetuximab in Head and Neck Squamous Cell Carcinoma (HNSCC)
Head and neck squamous cell carcinoma (HNSCC) is the most common malignancy group in India and several other low- and middle-income countries. Currently, majority of the patients present in advanced stage where systemic therapy is standard of care. Multiple relapses are also not uncommon. Almost all HNSCC tumors have epidermal growth factor receptor (EGFR) overexpression, making an attractive target. Cetuximab is the most successful method to target EGFR in HNSCC. After decades of its use, it still is a prominent part of the current management guidelines. Since other agents have also been proven to be useful, we felt it was necessary to develop a real-world consensus guideline to help the decision-making process among the community oncologists. Our expert committee therefore put together currently available data, insights from their real-world clinical practice, and voted to arrive at a consensus. These consensus guidelines represent how cetuximab should be used today in the management of HNSCC.
Authors
- Purvish M. Parikh (ORCID: https://orcid.org/0000-0003-3813-8788)
- Poonam Patil (ORCID: https://orcid.org/0000-0001-9518-2609)
- N. Dhamne
- Hemant Malhotra (ORCID: https://orcid.org/0000-0001-5613-5375)
- Arun Seshachalam (ORCID: https://orcid.org/0000-0002-8934-3696)
- Boman Dhabhar (ORCID: https://orcid.org/0000-0003-4872-1408)
- Govind Babu (ORCID: https://orcid.org/0000-0002-1303-2226)
- Prasad V.S.S. Sripada
- Ashish Kumar Singh (ORCID: https://orcid.org/0000-0003-3534-9010)
- Sewanti Atul Limaye (ORCID: https://orcid.org/0000-0001-6640-1470)
- Suhas Agre
- Ajay Sharma (ORCID: https://orcid.org/0000-0002-1555-1791)
- Ayesha B. Bhat (ORCID: https://orcid.org/0000-0002-0093-6031)
- Chetan Dilip Deshmukh
- Atul Sharma
- Suresh Hariram Advani
- Vikas Talreja (ORCID: https://orcid.org/0000-0002-1599-3047)
- Bhupendra Nath Kapur
- Niraj Bhatt
- Ghanashyam Biswas (ORCID: https://orcid.org/0000-0002-4855-9343)
- Pratap K. Das
- Priya Priyadarshini Nayak (ORCID: https://orcid.org/0009-0001-8421-3630)
- V. Maniar
Institutions
- Apollo Hospitals (IN)
- Christian Medical College, Vellore (IN)
- Mahatma Gandhi University (IN)
- Sir H.N. Reliance Foundation Hospital and Research Centre (IN)
- Cancer Institute (WIA) (IN)
- Max Healthcare (IN)
- Christian Medical College (IN)
- Sparsh Hospital (IN)
- Deenanath Mangeshkar Hospital and Research Center (IN)
- Fortis Hospital (IN)
- Yashoda Hospital (IN)
- Bombay Hospital (IN)
- St.John's Medical College Hospital (IN)
- Manipal Hospital (IN)
Publication Details
- Journal
- South Asian Journal of Cancer
- Published
- 2024-10-16
- DOI
- https://doi.org/10.1055/s-0044-1791783
- Citations
- 3
- Primary Topic
- Head and Neck Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.74