Altered B-cell, plasma cell, and antibody immune profiles in blood of patients with systemic mastocytosis
Our results reveal a significant dysregulation of the B-cell and PC compartments in blood of patients with SM, consistent with distinctly altered antibody isotype profiles in plasma of patients with BMM versus ISM versus ASM.
Authors
- Alba Pérez‐Pons (ORCID: https://orcid.org/0000-0002-5805-1391)
- Martín Pérez‐Andrés (ORCID: https://orcid.org/0000-0003-4599-0776)
- Andrés C. García‐Montero (ORCID: https://orcid.org/0000-0003-4360-1386)
- Andrea Mayado (ORCID: https://orcid.org/0000-0003-1498-7398)
- Óscar González‐López (ORCID: https://orcid.org/0000-0002-4169-4294)
- Rafael Fluxá
- María Jara‐Acevedo (ORCID: https://orcid.org/0000-0001-7965-7512)
- Iván Álvarez‐Twöse (ORCID: https://orcid.org/0000-0002-1190-4473)
- Quentin Lécrevisse (ORCID: https://orcid.org/0000-0001-8715-5846)
- Carolina Caldas (ORCID: https://orcid.org/0000-0003-3967-6211)
- Laura Sánchez‐Muñoz (ORCID: https://orcid.org/0000-0003-1757-7255)
- Paula Navarro‐Navarro
- Alberto Órfão (ORCID: https://orcid.org/0000-0002-0007-7230)
- Julio Pozo
- Ana Henriques (ORCID: https://orcid.org/0000-0002-5096-791X)
- Teresa Contreras Sanfeliciano
Institutions
- Universidad de Salamanca (ES)
- Hospital Virgen del Valle (ES)
- Instituto de Investigación Biomédica de Salamanca (ES)
- Centro de Investigación del Cáncer (ES)
Publication Details
- Journal
- Journal of Allergy and Clinical Immunology
- Published
- 2024-10-16
- DOI
- https://doi.org/10.1016/j.jaci.2024.10.005
- Citations
- 1
- Primary Topic
- Mast cells and histamine
- Type
- article
- Field-Weighted Citation Impact
- 0.24
Funders
- Ministerio de Ciencia, Innovación y Universidades
- Centro de Investigación Biomédica en Red de Cáncer
- Instituto de Salud Carlos III