The deubiquitinase OTUD3 stabilizes IRP2 expression to reduce hippocampal neuron ferroptosis via the p53/PTGS2 pathway to ameliorate cerebral ischemia–reperfusion injury
The deubiquitinase OTUD3 stabilized IRP2 expression to reduce hippocampal neuron ferroptosis via the p53/PTGS2 pathway to subsequently ameliorate cerebral I/R injury.
Authors
- Yun Tian (ORCID: https://orcid.org/0000-0003-1475-309X)
- Dan Hou (ORCID: https://orcid.org/0009-0003-9501-4180)
- Guoshuai Yang (ORCID: https://orcid.org/0000-0003-4824-9457)
- Yujie Hu (ORCID: https://orcid.org/0000-0002-1515-514X)
- Hongxin Li (ORCID: https://orcid.org/0000-0003-4940-1414)
- Dan Yu (ORCID: https://orcid.org/0000-0003-2114-1200)
Institutions
- Central South University (CN)
- Hainan University (CN)
- Beijing Forestry University (CN)
Publication Details
- Journal
- European journal of medical research
- Published
- 2024-10-17
- DOI
- https://doi.org/10.1186/s40001-024-02095-w
- Citations
- 6
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 2.51