Lipid droplet‐associated proteins in alcohol‐associated fatty liver disease: A proteomic approach
Several significantly altered proteins were identified in different-sized LDs isolated from livers of ethanol-fed rats. Ethanol-induced increases in specific proteins that hinder LD lipid metabolism led to the accumulation and persistence of large-sized LDs in the liver.
Authors
- Le Day (ORCID: https://orcid.org/0000-0002-2342-9323)
- Madan Kumar Arumugam (ORCID: https://orcid.org/0000-0003-0567-7857)
- Karuna Rasineni (ORCID: https://orcid.org/0000-0002-9581-3957)
- Natalia A. Osna (ORCID: https://orcid.org/0000-0001-7498-0556)
- Kusum K. Kharbanda (ORCID: https://orcid.org/0000-0001-7759-8889)
- Jon Jacobs (ORCID: https://orcid.org/0000-0003-0557-7338)
- Sathish Kumar Perumal (ORCID: https://orcid.org/0000-0003-0151-521X)
- Vikas Kumar (ORCID: https://orcid.org/0000-0001-7513-6832)
- Srinivas Chava
Institutions
- Pacific Northwest National Laboratory (US)
- Environmental Molecular Sciences Laboratory (US)
- VA Nebraska Western Iowa Health Care System (US)
- Sathyabama Institute of Science and Technology (IN)
- University of Nebraska Medical Center (US)
Publication Details
- Journal
- Alcohol Clinical and Experimental Research
- Published
- 2024-10-16
- DOI
- https://doi.org/10.1111/acer.15446
- Citations
- 5
- Primary Topic
- Lipid metabolism and biosynthesis
- Type
- article
- Field-Weighted Citation Impact
- 1.47
Funders
- Biomedical Laboratory Research and Development, VA Office of Research and Development
- National Institutes of Health