Targeting cancer-associated fibroblasts/tumor cells cross-talk inhibits intrahepatic cholangiocarcinoma progression via cell-cycle arrest
The hCAFs/iCCA cross-talk is a new target for reducing cancer progression with drugs such as Crenigacestat.
Authors
- Serena Mancarella (ORCID: https://orcid.org/0000-0003-2692-1169)
- Francesco Dituri (ORCID: https://orcid.org/0000-0002-7943-3698)
- Elena Antinoro Pizzuto (ORCID: https://orcid.org/0009-0002-9834-4356)
- Leonardo Vincenti (ORCID: https://orcid.org/0000-0002-8330-7889)
- Isabella Gigante (ORCID: https://orcid.org/0000-0003-3712-4149)
- Alberta Terzi (ORCID: https://orcid.org/0009-0000-3754-2928)
- Francesco Ardito (ORCID: https://orcid.org/0000-0003-1596-2862)
- Eugenio Maiorano (ORCID: https://orcid.org/0000-0002-0472-5338)
- Gianluigi Giannelli (ORCID: https://orcid.org/0000-0002-5140-8060)
- Grazia Serino (ORCID: https://orcid.org/0000-0002-2971-0802)
- Mario De Bellis (ORCID: https://orcid.org/0000-0001-7932-5921)
- Diego F. Calvisi (ORCID: https://orcid.org/0000-0002-6038-8567)
Institutions
- University of Verona (IT)
- Agostino Gemelli University Polyclinic (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- Gastroenterology Hospital "Saverio de Bellis" (IT)
- University of Regensburg (DE)
Publication Details
- Journal
- Journal of Experimental & Clinical Cancer Research
- Published
- 2024-10-17
- DOI
- https://doi.org/10.1186/s13046-024-03210-9
- Citations
- 8
- Primary Topic
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 4.58
Funders
- Ministero della Salute
- Associazione Italiana per la Ricerca sul Cancro