Undetectable pre‐radical cystectomy circulating tumour <scp>DNA</scp> status predicts improved oncological outcomes
Patients with undetectable pre-RC ctDNA status have a favourable prognosis and may be candidates for treatment de-escalation. Those with persistently undetectable ctDNA had superior RFS compared to the conversion group. Pre-RC ctDNA status should be incorporated into trials examining ctDNA use in clinical decision-making.
Authors
- Peter N. Wiklund (ORCID: https://orcid.org/0000-0001-6497-4697)
- Reuben Ben‐David (ORCID: https://orcid.org/0000-0001-7946-7145)
- Kyrollis Attalla (ORCID: https://orcid.org/0000-0002-4707-9663)
- Neeraja Tillu (ORCID: https://orcid.org/0000-0002-4149-0486)
- Basil Kaufmann (ORCID: https://orcid.org/0000-0001-6965-449X)
- John P. Sfakianos (ORCID: https://orcid.org/0000-0002-3101-0266)
- Reza Mehrazin (ORCID: https://orcid.org/0009-0007-8648-0410)
- Jack Geduldig
- Asher Mandel (ORCID: https://orcid.org/0000-0001-8529-6792)
- Yuval Elkun (ORCID: https://orcid.org/0000-0001-7181-9783)
- Sarah Lidagoster
- Kaushik P. Kolanukuduru (ORCID: https://orcid.org/0009-0001-9525-2600)
- Mohammed Almoflihi
Institutions
- Icahn School of Medicine at Mount Sinai (US)
Publication Details
- Journal
- British Journal of Urology
- Published
- 2024-10-16
- DOI
- https://doi.org/10.1111/bju.16556
- Citations
- 6
- Primary Topic
- Bladder and Urothelial Cancer Treatments
- Type
- article
- Field-Weighted Citation Impact
- 3.44