The role and mechanism of NRG1/ErbB4 in inducing the differentiation of induced pluripotent stem cells into cardiomyocytes
In conclusion, promoting the expression of NRG1/ErbB4 induced the differentiation of iPSC into cardiomyocytes, possibly through modulation of the PI3K/Akt signaling pathway.
Authors
- Heng Zhang (ORCID: https://orcid.org/0000-0003-0198-7882)
- Hong Jiang (ORCID: https://orcid.org/0000-0003-2812-4120)
- Wenjing Li (ORCID: https://orcid.org/0009-0009-7419-9124)
- Hu Tuo (ORCID: https://orcid.org/0009-0009-5225-0267)
- Bing He (ORCID: https://orcid.org/0000-0003-1476-0986)
- Xiaoou Li
Institutions
- Wuhan University (CN)
- Renmin Hospital of Wuhan University (CN)
Publication Details
- Journal
- BMC Cardiovascular Disorders
- Published
- 2024-10-16
- DOI
- https://doi.org/10.1186/s12872-024-04224-z
- Primary Topic
- Pluripotent Stem Cells Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00