An Investigation of the Effect of Garcina kola (Heckel) and Cola nitida (Vent.) Schott & Endl. on Sperm Motility with Two Vital Organs of Male Wistar Rats

A total number of 30 Wistar rats were used for the experiment and acclimatized for two weeks prior to the commencement of the consumption of the seeds (Garcinia kola and Cola nitida). The rats were grouped into four (4) groups A, B C and D. Group A serves as the control having just 5rats which were fed with feeds without any treatment. Group B contained 15 rats feed with Garcinia kola seeds orally and the rats in this group were sub divided into 3 sub-groups having 5 rats each which were feed varying amounts of Garcinia kola seeds in 25kg, 50kg and 75kg concentration per subgroup. These same procedures were applied to Group C which was feed with Cola nitida in the same variation as group B. However, group D were feed with an average combination of both Garcinia kola and Cola nitida meaning that for 25kg treatment concentration, 12.5kg of each powdered seeds were used and likewise for the 50kg and 75kg treatment concentrations. The animals were feed in these rotations for 6weeks. The weight of each rat were measured and recorded at the end of each week. At the end of the treatments, the Wistar albino rats were sacrifice by cervical dislocation to test for the effect of the treatment on the Full Blood Count, Liver, Kidney and Sperm. The results showed that ingestion of G. Kola seed resulted in significantly reduced sperm count, motility, mild changes in the full blood count and abnormalities present in the liver and kidney.