Evaluation of coinfection between SARS-CoV-2 and dengue virus in São Luís/MA
The COVID-19 pandemic has become a global public health emergency, especially in subtropical regions endemic for arboviruses. During the acute phase of the disease, Dengue and COVID-19 present similar laboratory profiles and symptomatology, complicating clinical diagnosis. This study analyzed the occurrence of coinfections between dengue virus and SARS-CoV-2 in patients treated at a laboratory in São Luís, Maranhão. A total of 150 random serum samples from patients, collected between April and May 2020, tested positive for IgM/IgA antibodies against SARS-CoV-2. For the detection of dengue virus (DENV), reactions were standardized using specific primers for each serotype (1-4). Subsequently, cDNA amplification was performed by conventional PCR, and the amplicons were analyzed by agarose gel electrophoresis. Through this study, it was possible to identify one sample (0.6%) positive for the DENV-4 serotype. This study validates the possibility of coinfections in dengue-endemic areas.
Authors
- Karinny Farias Silva (ORCID: https://orcid.org/0000-0002-2763-3452)
- Maria Rosa Quaresma Bomfim (ORCID: https://orcid.org/0000-0001-5738-3952)
- Luís Cláudio Nascimento da Silva
- Andrea de Souza Monteiro (ORCID: https://orcid.org/0000-0001-6887-8192)
- Bruna de Oliveira de Melo (ORCID: https://orcid.org/0000-0001-7617-0813)
- Douglas Henrique dos Santos Silva (ORCID: https://orcid.org/0000-0002-2669-1845)
- Lídio Gonçalves Lima Neto (ORCID: https://orcid.org/0000-0001-7282-3047)
- Valdenice F. Santos
Publication Details
- Journal
- Caderno Pedagógico
- Published
- 2024-10-16
- DOI
- https://doi.org/10.54033/cadpedv21n11-005
- Primary Topic
- Mosquito-borne diseases and control
- Type
- article
- Field-Weighted Citation Impact
- 0.00