UCF101 Rescues against Diabetes-Evoked Cardiac Remodeling and Contractile Anomalies through AMP-Activated Protein Kinase-Mediated Induction of Mitophagy
These findings suggest that UCF101 rescues diabetes-mediated alterations in cardiac structure and function, likely through AMPK-mediated regulation of mitophagy.
Authors
- Jun Tao (ORCID: https://orcid.org/0000-0003-2899-0248)
- Chaohui Dong (ORCID: https://orcid.org/0000-0002-7741-0142)
- Jun Ren (ORCID: https://orcid.org/0000-0002-0275-0783)
- Yuxi Zhu (ORCID: https://orcid.org/0000-0001-7563-505X)
- Xing Qin (ORCID: https://orcid.org/0000-0003-1119-9740)
- Zhaohui Pei
- Zhiqiang Zhuang (ORCID: https://orcid.org/0009-0007-7136-7722)
- Qun Li (ORCID: https://orcid.org/0000-0002-9128-5405)
- Jie Lin (ORCID: https://orcid.org/0000-0003-3535-5250)
- Yandong Liu (ORCID: https://orcid.org/0000-0002-4752-9484)
- Guizhen Wang (ORCID: https://orcid.org/0000-0002-7333-6803)
- Chunjie Yang (ORCID: https://orcid.org/0000-0002-2018-6557)
- Russel J. Reiter
Institutions
- Tongji University (CN)
- Sun Yat-sen University (CN)
- The University of Texas at San Antonio Health Science Center (US)
- Fudan University (CN)
- Regenex Pharmaceuticals (China) (CN)
- Sun Yat-sen Memorial Hospital (CN)
- Air Force Engineering University (CN)
- Second Hospital of Nanchang (CN)
- Zhongshan Hospital (CN)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
- Shanghai Tenth People's Hospital (CN)
- Southern Medical University (CN)
- The University of Texas Health Science Center at Houston (US)
Publication Details
- Journal
- Pharmacology
- Published
- 2024-10-16
- DOI
- https://doi.org/10.1159/000541569
- Citations
- 6
- Primary Topic
- Autophagy in Disease and Therapy
- Type
- article
- Field-Weighted Citation Impact
- 2.32